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2024-11-19

FISH: Differentiation between aneugens and clastogens in in vitro micronucleus tests

In in vitro micronucleus tests (according to OECD 487), the occurrence of micronuclei in interphase cells provides an indirect, but easy and rapid measurement of structural chromosomal damage (clastogenicity) and effects on the spindle apparatus (aneugenicity) in cells that have undergone cell division during or after exposure to a test substance. Micronuclei arise from chromosomal fragments or whole chromosomes, occur rarely spontaneously, but are induced by clastogenic or aneugenic agents.

2024-11-14

Swiss company NIUTEC becomes a new member of the GBA Group

The GBA Group is expanding its international laboratory network and is represented in Switzerland for the first time with the addition of laboratory service provider NIUTEC AG (NIUTEC). With this acquisition, the GBA Group is once again strengthening its positioning in the growing market for the qualification of medical devices. Furthermore, the partnership with NIUTEC creates a strong basis for further development in the important local Swiss market for environmental analysis.

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GBA Group is an international life science service company with more than 3,000 employees and a broad range of analytical, logistical and specialist services in the fields of pharmaceuticals, medical products, cosmetics, chemicals, food, drinking water and the environmental sustainability.

The range of services offered by the GBA Group includes laboratory analytics, data management, special logistical services for clinical trials, as well as consulting services for private companies and public institutions in connection with their activities in the fields of research, product development, market development, and consumer protection.

Through its work, the GBA Group makes a sustainable contribution to public health, the environment and society as a whole.

The GBA Group operates sites in Austria, Belgium, Denmark, Finland, France, Germany, Netherlands, Poland, Switzerland, Sweden, Spain, India and the United States.

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